Biomax Symposium 2014

Translating Systems Medicine into Practice

Download the position paper outlining the common themes presented at this year’s symposium.

Implementing systems medicine within healthcare
Kirschner M, Bauch A, Agusti A, Hilke S, Merk S, Pison C, Roldan J, Seidenath B, Wilken M, Wouters EF, Mewes HW, Heumann K and Maier D (2015) Genome Medicine 7:102 Abstract
Full text

The 2014 Biomax Symposium on Translating Systems Medicine into Practice, co-hosted by CASyM, addressed the challenges and opportunities of using systems medicine in diverse healthcare settings. Representatives from healthcare, clinics, medical research, patient organizations and government came together in Martinsried, Germany on September 5th, 2014 to exchange experiences, learn from each other and discuss the way forward in realizing systems medicine in real healthcare settings.

Read more

The symposium speakers presented examples of how systems medicine is transforming medical research and clinical practice today, such as the approach developed and implemented at CIRO, the Center of Expertise for Chronic Organ Failure in The Netherlands. This and other case studies highlighted the opportunities offered by integrating knowledge from various healthcare aspects including patient care, clinical data, changes in lifestyle and environmental factors as well as cost-saving clinical management strategies. The program presented by CIRO uses the BioXM™ system as a central knowledge management environment for patient stratification and targeted therapy. It provides a blueprint that can be applied to different disease areas and clinic settings.

A discussion forum addressed the challenges of implementing systems medicine programs and gave participants the opportunity to ask managers in the clinic, government representatives and patient advocates as well as state and European organizations, like the Bayerische Telemed Allianz (Bavarian Telemed Alliance) and CASyM (the European consortium for Coordinating Action Systems Medicine), for their perspectives.

Symposium participants were also able to delve deeper in practical know-how sessions exploring the use of knowledge management, data mining and other methods used to realize systems medicine in practice.

The symposium position paper, Implementing systems medicine within healthcare, outlines the common themes presented at the symposium and offers expert advice on putting systems medicine strategies into practice.

Speakers and presentations:

KLAUS HEUMANN (Biomax Informatics AG)
“Introduction”

DIETER MAIER (Biomax Informatics AG)
“Translating Systems Medicine into Practice”

PART I: CLINICAL SYSTEMS

EMIEL WOUTERS (Medical University, Maastricht, The Netherlands)
“Towards Personalized and Systems Medicine in COPD: the CIRO Experience”

CHRISTOPHE PISON (Clinique Universitaire de Pneumologie, Grenoble, France)
“Prediction of Chronic Lung Allograft Dysfunction: A Systems Medicine Challenge”
This presentation is not publicly available.
Please contact Biomax for more information.

Àlvar Agustí (Thorax Institute, Barnaclinic+, Barcelona, Spain)
“Systemic inflammatory Response to Smoking”
This presentation is not publicly available.
Please contact Biomax for more information.

PART II: TRANSLATION BEYOND THE CLINIC

DIANE LEFAUDEUX (European Institute for Systems Biology and Medicine, Lyon, France)
“U-BIOPRED Toolbox for Fingerprint and Handprint Discovery”

JAN GEURTS (FrieslandCampina, Amersfoort, The Netherlands)
“A Comprehensive Approach to Nutrition for Health Maintenance”

HANS-WERNER MEWES (Helmholtz-Center, Munich, Germany)
“Paradigms and Needs in Systems Medicine”

PART III: SYSTEMS MEDICINE TECHNICAL HOW-TO

ZLATKO TRAJANOSKI (Medical University, Division of Bioinformatics, Innsbruck, Austria)
“Bioinformatics for Cancer Immunology and Immunotherapy”

JIM ROLDAN (Linkcare Health Services, Barcelona, Spain)
“Knowledge as a Service (KaaS)”

The afternoon discussion forum addressed the challenges of implementing systems medicine programs. Participants took advantage of the opportunity to ask managers in the clinic, government representatives and patient advocates from the Deutsche Patientenliga Atemwegserkrankungen e.V. as well as state and European organizations such as the Bayerische Telemed Allianz (Bavarian Telemed Allicance) and CASyM (European Consortium for Coordinating Action Systems Medicine) for their perspectives.

What are the challenges and opportunities of systems medicine?
How can systems medicine be realized in practice?

Thank you to all our panel members:

  • Michael Wilken, Deutsche Patientenliga, gave insights on the patient point of view
  • Sibylle Merk from Passauer Wolf Reha centers gave the perspective of clinic management
  • Marc Kirschner, CASyM (European Consortium for Coordinating Action Systems Medicine), spoke of the CASyM roadmap for implementing systems medicine
  • Sebastian Hilke from the Bayerische TelemedAllianz gave insights into telemedicine activities in Bavaria
  • Bernhard Seidenath, MdL, Gesundheitspolitischer Sprecher CSU, offered a governmental perspective

The workshop sessions delved deeper into specific topics and included hands-on demonstrations.

Session 1: The CIRO clinical systems
From the perspective of a clinical-research organization with expertise in chronic organ failure, Dr. Jan Kirrbach, showed how the BioXM platform currently provides a computational and conceptual infrastructure. The platform enables integration and analysis of diverse clinical data, and ultimately, patient stratification resulting in the delivery of improved individualized patient care.

Session 2: Viscovery® visual data mining
Dr. Gerhard Kranner, Viscovery Software GmbH (a part of the Biomax Group), presented various applications of the software data mining suite including instruments used for visual data exploration, cluster analysis and profiling of complex data.

Session 3: BioXM™ technology
Dr. Sascha Losko, Biomax Informatics, delivered a “BioXM 101” workshop, which demonstrated the features of the system with a case-driven overview of different BioXM modules. The latest new features provided in the most recent release were also highlighted.

Copyright © 1997-2017 | Biomax Informatics AG | Headquarters in Planegg, Germany | +49 89 89 55 74-0