Publications from Prof. Dr. Mewes (since 1992)

  1. Ellwanger DC, Büttner FA, Mewes HW and Stümpflen V (2011) The sufficient minimal set of miRNA seed types. Bioinformatics 27(10):1346–50
  2. Mewes HW, Ruepp A, Theis F, Rattei T, Walter M, Frishman D, Suhre K, Spannagl M, Mayer KFX, Stumpflen V and Antonov A (2011) MIPS: curated databases and comprehensive secondary data resources in 2010. Nucleic Acids Res 39 (Database issue):D220–4
  3. Tretter F, Gebicke-Haerter PJ, an der Heiden U, Rujescu D, Mewes HW and Turck CW (2011) Affective disorders as complex dynamic diseases — a perspective from systems biology. Pharmacopsychiatry 44 (Suppl 1):2–S8
  4. Wong P, Walter M, Lee W, Mannhaupt G, Münsterkötter M, Mewes HW, Adam G and Güldener U (2011) FGDB: revisiting the genome annotation of the plant pathogen Fusarium graminearum. Nucleic Acids Res 39 (Database issue):D637–9
  5. Büttner F, Ellwanger D, Mewes HW and Stümpflen V (2010) Large scale analysis reveals novel insights in the characteristics of miRNA targeting. In Schomburg D and Grote A, eds. Lecture Notes in Informatics. Gesellschaft für Informatik, Bonn
  6. Haack TB, Danhauser K, Haberberger B, Hoser J, Strecker V, Boehm D, Uziel G, Lamantea E, Invernizzi F, Poulton J, Rolinski B, Iuso A, Biskup S, Schmidt T, Mewes HW, Wittig I, Meitinger T, Zeviani M and Prokisch H (2010) Exome sequencing identifies ACAD9 mutations as a cause of complex I deficiency. Nat Genet 42(12):1131–4
  7. Illig T, Gieger C, Zhai G, Römisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmueller G, Kato BS, Mewes HW, Meitinger T, de Angelis MH, Kronenberg F, Soranzo N, Wichmann HE, Spector TD, Adamski J and Suhre K (2010) A genome-wide perspective of genetic variation in human metabolism. Nat Genet 42(2):137–41
  8. Mewes HW, Wachinger B and Stümpflen V (2010) Perspectives of a systems biology of the synapse: how to transform an indefinite data space into a model? Pharmacopsychiatry 43(S1): S2–S8
  9. Rattei T, Tischler P, Götz S, Jehl MA, Hoser J, Arnold R, Conesa A and Mewes HW (2010) SIMAP, a comprehensive database of pre-calculated protein sequence similarities, domains, annotations and clusters. Nucleic Acids Res 38 (Database issue):D223–6
  10. Ruepp A, Waegele B, Lechner M, Brauner B, Dunger-Kaltenbach I, Fobo G, Frishman G, Montrone C and Mewes HW (2010) CORUM: the comprehensive resource of mammalian protein complexes - 2009. Nucleic Acids Res 38 (Database issue):D497–501
  11. Suhre K et al (2010) Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS One 5(11): e13953
  12. Antonov AV, Dietmann S, Wong P, Rodchenkov I and Mewes HW (2009) PLIPS, an automatically collected database of protein lists reported by proteomics studies. J Proteome Res 8(3):1193–7
  13. Antonov AV, Dietmann S, Wong P and Mewes HW (2009) TICL — a web tool for network-based interpretation of compound lists inferred by high-throughput metabolomics. FEBS J 276(7):2084–94
  14. Antonov AV, Dietmann S, Rodchenkov I and Mewes HW (2009) PPI spider: A tool for the interpretation of proteomics data in the context of protein-protein interaction networks. Proteomics 9(10):2740–9
  15. Antonov AV, Dietmann S, Wong P, Lutter D and Mewes HW (2009) GeneSet2miRNA: finding the signature of cooperative miRNA activities in the gene lists. Nucleic Acids Res 37 (Web Server issue):W323–8
  16. Apweiler R et al (2009) Approaching clinical proteomics: current state and future fields of application in fluid proteomics. Clin Chem Lab Med 47(6):724–44
  17. Apweiler R et al (2009) Approaching clinical proteomics: current state and future fields of application in cellular proteomics. Cytometry A 75(10):816–32
  18. Arnold R, Brandmaier S, Kleine F, Tischler P, Heinz E, Behrens S, Niinikoski A, Mewes HW, Horn M and Rattei T (2009) Sequence-based prediction of type III secreted proteins. PloS Pathog 5(4): e1000376
  19. Barnickel T, Weston J, Collobert R, Mewes HW and Stümpflen V (2009) Large scale application of neural network based semantic role labeling for automated relation extraction from biomedical texts. PloS One 4(7):e6393
  20. Dietmann S, Georgii E, Antonov A, Tsuda K and Mewes HW (2009) The DICS repository: module-assisted analysis of disease-related gene lists. Bioinformatics 25(6):830–1
  21. Kastenmüller G, Schenk ME, Gasteiger J and Mewes HW (2009) Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes. Genome Biol 10:R28
  22. Schmidt T, Mewes HW and Stuempflen V (2009) A novel putative miRNA target enhancer signal. PloS One 4(7):e6473
  23. Waegele B, Dunger-Kaltenbach I, Fobo G, Montrone C, Mewes HW and Ruepp A (2009) CRONOS: the cross-reference navigation server. Bioinformatics 25(1):141–3
  24. Walter MC, Rattei T, Arnold R, Güldener U, Münsterkötter M, Nenova K,Kastenmüller G, Tischler P, Wölling A, Volz A, Pongratz N, Jost R, Mewes HW and Frishman D (2009) PEDANT covers all complete RefSeq genomes. Nucleic Acids Res 37 (Database issue):D408–11
  25. Antonov AV, Dietmann S and Mewes HW (2008) KEGG spider: interpretation of genomics data in the context of the global gene metabolic network. Genome Biol 9(12):R179
  26. Gieger C et al (2008) Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PloS Genet 4(11):e1000282
  27. Antonov AV and Mewes HW (2008) Complex phylogenetic profiling reveals fundamental genotype-phenotype associations. Comput Biol Chem 32(6):412–6
  28. Kuhn KA et al (2008) Informatics and medicine — from molecules to populations. Methods Inf Med 47(4):283–95
  29. Kastenmüller G, Gasteiger J and Mewes HW (2008) An environmental perspective on large-scale genome clustering based on metabolic capabilities. Bioinformatics 24(16):i56–62
  30. Surmeli D, Ratmann O, Mewes HW and Tetko IV (2008) FunCat functional inference with belief propagation and feature integration. Comput Biol Chem 32(5):375–7
  31. Waegele B, Schmidt T, Mewes HW and Ruepp A (2008) OREST: the online resource for EST analysis. Nucleic Acids Res 36 (Web Server issue):W140–4
  32. Antonov AV, Schmidt T, Wang Y and Mewes HW (2008) ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data. Nucleic Acids Res 36 (Web Server issue):W347–51
  33. Altmaier E, Ramsay SL, Graber A, Mewes HW, Weinberger KM and Suhre K (2008) Bioinformatics analysis of targeted metabolomics — uncovering old and new tales of diabetic mice under medication. Endocrinology 149(7):3478-89
  34. Ruepp A, Brauner B, Dunger-Kaltenbach I, Frishman G, Montrone C, Stransky M, Waegele B, Schmidt T, Doudieu ON, Stuempflen V and Mewes HW (2008) CORUM: the comprehensive resource of mammalian protein complexes. Nucleic Acids Res 36:D646–50
  35. Rattei T, Tischler P, Arnold R, Hamberger F, Krebs J, Krumsiek J, Wachinger B, Stumpflen V and Mewes W (2008) SIMAP — structuring the network of protein similarities. Nucleic Acids Res 36:D289–92
  36. Mewes HW, Dietmann S, Frishman D, Gregory R, Mannhaupt G, Mayer KF, Muensterkoetter M, Ruepp A, Spannagl M, Stuempflen V and Rattei T (2008) MIPS: analysis and annotation of genome information in 2007. Nucleic Acids Res 36:D196–201
  37. Tetko IV, Rodchenkov IV, Walter MC, Rattei T and Mewes HW (2008) Beyond the "Best" Match: Machine Learning Annotation of Protein Sequences by Integration of Different Sources of Information. Bioinformatics 24(5):621–8
  38. Orchard S et al (2007) The minimum information required for reporting a molecular interaction experiment (MIMIx). Nat Biotechnol 25(8):894–8
  39. Emmersen J, Rudd S, Mewes HW and Tetko IV (2007) Separation of sequences from host-pathogen interface using triplet nucleotide frequencies. Fungal Genet Biol 44(4):231–41
  40. Cuomo CA et al (2007) The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization. Science 317(5843):1400–2
  41. Riley ML, Schmidt T, Artamonova II, Wagner C, Volz A, Heumann K, Mewes HW and Frishman D (2007) PEDANT genome database: 10 years online. Nucleic Acids Res 35 (Database issue):D354–7
  42. Kämper J et al (2006) Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis. Nature 444:97–101
  43. Dietmann S, Aguilar D, Mader M, Oesterheld M, Ruepp A, Stuempflen V and Mewes HW (2006) Resources and tools for investigating biomolecular networks in mammals. Curr Pharm Des 12:3723–34
  44. Antonov AV and Mewes HW (2006) Complex functionality of gene groups identified from high-throughput data. J Mol Biol 363(1):289–96
  45. Tetko IV, Bruneau P, Mewes HW, Rohrer DC and Poda GI (2006) Can we estimate the accuracy of ADME-Tox predictions? Drug Discov Today 11:700–7
  46. Guldener U, Seong KY, Boddu J, Cho S, Trail F, Xu JR, Adam G, Mewes HW, Muehlbauer GJ and Kistler HC (2006) Development of a Fusarium graminearum Affymetrix GeneChip for profiling fungal gene expression in vitro and in planta. Fungal Genet Biol 43:316–25
  47. Strous M, Pelletier E, Mangenot S, Rattei T, Lehner A, Taylor MW, Horn M, Daims H, Bartol-Mavel D, Wincker P, Barbe V, Fonknechten N, Vallenet D, Segurens B, Schenowitz-Truong C, Medigue C, Collingro A, Snel B, Dutilh BE, Op den Camp HJ, van der Drift C, Cirpus I, van de Pas-Schoonen KT, Harhangi HR, van Niftrik L, Schmid M, Keltjens J, van de Vossenberg J, Kartal B, Meier H, Frishman D, Huynen MA, Mewes HW, Weissenbach J, Jetten MS, Wagner M and Le Paslier D (2006) Deciphering the evolution and metabolism of an anammox bacterium from a community genome. Nature 440:790–4
  48. Bhonde MR, Hanski ML, Budczies J, Cao M, Gillissen B, Moorthy D, Simonetta F, Scherubl H, Truss M, Hagemeier C, Mewes HW, Daniel PT, Zeitz M and Hanski C (2006) DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis. J Biol Chem 281:8675–85
  49. Tetko IV, Haberer G, Rudd S, Meyers B, Mewes HW and Mayer KF (2006) Spatiotemporal expression control correlates with intragenic scaffold matrix attachment regions (S/MARs) in Arabidopsis thaliana. PLoS Comput Biol 2:e21
  50. Antonov AV and Mewes HW (2006) BIOREL: the benchmark resource to estimate the relevance of the gene networks. FEBS Lett 580:844–8
  51. Antonov AV, Tetko IV and Mewes HW (2006) A systematic approach to infer biological relevance and biases of gene network structures. Nucleic Acids Res 34:e6
  52. Ruepp A, Doudieu ON, van den Oever J, Brauner B, Dunger-Kaltenbach I, Fobo G, Frishman G, Montrone C, Skornia C, Wanka S, Rattei T, Pagel P, Riley L, Frishman D, Surmeli D, Tetko IV, Oesterheld M, Stumpflen V and Mewes HW (2006) The Mouse Functional Genome Database (MfunGD): functional annotation of proteins in the light of their cellular context. Nucleic Acids Res 34:D568–71
  53. Guldener U, Mannhaupt G, Munsterkotter M, Haase D, Oesterheld M, Stumpflen V, Mewes HW and Adam G (2006) FGDB: a comprehensive fungal genome resource on the plant pathogen Fusarium graminearum. Nucleic Acids Res 34:D456–8
  54. Guldener U, Munsterkotter M, Oesterheld M, Pagel P, Ruepp A, Mewes HW and Stumpflen V (2006) MPact: the MIPS protein interaction resource on yeast. Nucleic Acids Res 34:D436–41
  55. Rattei T, Arnold R, Tischler P, Lindner D, Stumpflen V and Mewes HW (2006) SIMAP: the similarity matrix of proteins. Nucleic Acids Res 34:D252–6
  56. Mewes HW, Frishman D, Mayer KF, Munsterkotter M, Noubibou O, Pagel P, Rattei T, Oesterheld M, Ruepp A and Stumpflen V (2006) MIPS: analysis and annotation of proteins from whole genomes in 2005. Nucleic Acids Res 34:D169–72
  57. Antonov AV, Tetko IV, Kosykh D, Surmeli D and Mewes HW (2006) Exploiting scale-free information from expression data for cancer classification. Comput Biol Chem 29:288–93
  58. Tetko IV, Brauner B, Dunger-Kaltenbach I, Frishman G, Montrone C, Fobo G, Ruepp A, Antonov AV, Surmeli D and Mewes HW (2006) MIPS bacterial genomes functional annotation benchmark dataset. Bioinformatics 21:2520–1
  59. Friedel CC, Jahn KH, Sommer S, Rudd S, Mewes HW and Tetko IV (2006) Support vector machines for separation of mixed plant-pathogen EST collections based on codon usage. Bioinformatics 21:1383–8
  60. Tetko IV, Facius A, Ruepp A and Mewes HW (2006) Super paramagnetic clustering of protein sequences. BMC Bioinformatics 6:82
  61. Pagel P, Kovac S, Oesterheld M, Brauner B, Dunger-Kaltenbach I, Frishman G, Montrone C, Mark P, Stumpflen V, Mewes HW, Ruepp A and Frishman D (2005) The MIPS mammalian protein-protein interaction database. Bioinformatics 21:832–4
  62. Wang Y, Tetko IV, Hall MA, Frank E, Facius A, Mayer KF and Mewes HW (2005) Gene selection from microarray data for cancer classification—a machine learning approach. Comput Biol Chem 29:37–46
  63. Guldener U, Munsterkotter M, Kastenmuller G, Strack N, van Helden J, Lemer C, Richelles J, Wodak SJ, Garcia–Martinez J, Perez–Ortin JE, Michael H, Kaps A, Talla E, Dujon B, Andre B, Souciet JL, De Montigny J, Bon E, Gaillardin C and Mewes HW (2005) CYGD: the Comprehensive Yeast Genome Database. Nucleic Acids Res 33:D364–8
  64. Riley ML, Schmidt T, Wagner C, Mewes HW and Frishman D (2005) The PEDANT genome database in 2005. Nucleic Acids Res 33:D308–10
  65. Antonov AV, Tetko IV, Prokopenko VV, Kosykh D and Mewes HW (2004) A web portal for classification of expression data using maximal margin linear programming. Bioinformatics 20:3284–5
  66. Ruepp A, Zollner A, Maier D, Albermann K, Hani J, Mokrejs M, Tetko I, Guldener U, Mannhaupt G, Munsterkotter M and Mewes HW (2004) The FunCat, a functional annotation scheme for systematic classification of proteins from whole genomes. Nucleic Acids Res 32:5539–45
  67. Imanishi T et al (2004) Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol 2:e162
  68. Horn M, Collingro A, Schmitz-Esser S, Beier CL, Purkhold U, Fartmann B, Brandt P, Nyakatura GJ, Droege M, Frishman D, Rattei T, Mewes HW and Wagner M (2004) Illuminating the evolutionary history of chlamydiae. Science 304:728–30
  69. Antonov AV, Tetko IV, Mader MT, Budczies J and Mewes HW (2004) Optimization models for cancer classification: extracting gene interaction information from microarray expression data. Bioinformatics 20:644–52
  70. Pagel P, Mewes HW and Frishman D (2004) Conservation of protein-protein interactions — lessons from ascomycota. Trends Genet 20:72–6
  71. Crass T et al (2004) The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources. Bioinformatics 20:268–70
  72. Schoof H, Ernst R, Nazarov V, Pfeifer L, Mewes HW and Mayer KF (2004) MIPS Arabidopsis thaliana Database (MAtDB): an integrated biological knowledge resource for plant genomics. Nucleic Acids Res 32:D373–6
  73. Mewes HW, Amid C, Arnold R, Frishman D, Guldener U, Mannhaupt G, Munsterkotter M, Pagel P, Strack N, Stumpflen V, Warfsmann J and Ruepp A (2004) MIPS: analysis and annotation of proteins from whole genomes. Nucleic Acids Res 32:D41–4
  74. Tornow S and Mewes HW (2003) Functional modules by relating protein interaction networks and gene expression. Nucleic Acids Res 31:6283–9
  75. Mannhaupt G, Montrone C, Haase D, Mewes HW, Aign V, Hoheisel JD, Fartmann B, Nyakatura G, Kempken F, Maier J and Schulte U (2003) What's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence. Nucleic Acids Res 31:1944–54
  76. Bon E, Casaregola S, Blandin G, Llorente B, Neuveglise C, Munsterkotter M, Guldener U, Mewes HW, Van Helden J, Dujon B and Gaillardin C (2003) Molecular evolution of eukaryotic genomes: hemiascomycetous yeast spliceosomal introns. Nucleic Acids Res 31:1121–35
  77. Frishman D, Mokrejs M, Kosykh D, Kastenmuller G, Kolesov G, Zubrzycki I, Gruber C, Geier B, Kaps A, Albermann K, Volz A, Wagner C, Fellenberg M, Heumann K and Mewes HW (2003) The PEDANT genome database. Nucleic Acids Res 31:207–11
  78. Rudd S, Mewes HW and Mayer KF (2003) Sputnik: a database platform for comparative plant genomics. Nucleic Acids Res 31:128–32
  79. Kolesov G, Mewes HW and Frishman D (2002) SNAPper: gene order predicts gene function. Bioinformatics 18:1017–9
  80. Morgenstern B, Rinner O, Abdeddaim S, Haase D, Mayer KF, Dress AW and Mewes HW (2002) Exon discovery by genomic sequence alignment. Bioinformatics 18:777–87
  81. Mayer K and Mewes HW (2002) How can we deliver the large plant genomes? Strategies and perspectives. Curr Opin Plant Biol 5:173–7
  82. Schulte U, Becker I, Mewes HW and Mannhaupt G (2002) Large scale analysis of sequences from Neurospora crassa. J Biotechnol 94:3–13
  83. Frishman D, Kaps A and Mewes HW (2002) Online genomics facilities in the new millennium. Pharmacogenomics 3:265–71
  84. Schoof H, Zaccaria P, Gundlach H, Lemke K, Rudd S, Kolosov G, Arnold R, Mewes HW and Mayer KF (2002) MIPS Arabidopsis thaliana Database (MAtDB): an integrated biological knowledge resource based on the first complete plant genome. Nucleic Acids Res 30:91–3
  85. Wu CH et al (2002) The Protein Information Resource: an integrated public resource of functional annotation of proteins. Nucleic Acids Res 30:35–7
  86. Mewes HW, Frishman D, Guldener U, Mannhaupt G, Mayer K, Mokrejs M, Morgenstern B, Munsterkotter M, Rudd S and Weil B (2002) MIPS: a database for genomes and protein sequences. Nucleic Acids Res 30:31–4
  87. Kolesov G, Mewes HW and Frishman D (2001) SNAPping up functionally related genes based on context information: a colinearity-free approach. J Mol Biol 311:639–56
  88. Mayer K et al (2001) Conservation of microstructure between a sequenced region of the genome of rice and multiple segments of the genome of Arabidopsis thaliana. Genome Res 11:1167–74
  89. Geier B, Kastenmuller G, Fellenberg M, Mewes HW and Morgenstern B (2001) The HIB database of annotated UniGene clusters. Bioinformatics 17:571–2
  90. Weimann S et al (2001) Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Genome Res 11:422–35
  91. Bevan M, Mayer K, White O, Eisen JA, Preuss D, Bureau T, Salzberg SL and Mewes HW (2001) Sequence and analysis of the Arabidopsis genome. Curr Opin Plant Biol 4:105–10
  92. Frishman D, Albermann K, Hani J, Heumann K, Metanomski A, Zollner A and Mewes HW (2001) Functional and structural genomics using PEDANT. Bioinformatics 17:44–57
  93. Barker WC et al (2001) Protein Information Resource: a community resource for expert annotation of protein data. Nucleic Acids Res 29:29–32
  94. Tabata S et al (2000) Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature 408:823–6
  95. Salanoubat M et al (2000) Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Nature 408:820–2
  96. Ruepp A, Graml W, Santos-Martinez ML, Koretke KK, Volker C, Mewes HW, Frishman D, Stocker S, Lupas AN and Baumeister W (2000) The genome of the thermoacidophilic scavengerThermoplasma acidophilum. Nature 407:508–13
  97. Fellenberg M, Albermann K, Zollner A, Mewes HW and Hani J (2000) Integrative analysis of protein interaction data. Proc Int Conf Intell Syst Mol Biol 8:152–61
  98. Mayer K et al (1999) Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature 402:769–77
  99. Scharfe C et al (2000) MITOP, the mitochondrial proteome database: 2000 update. Nucleic Acids Res 28:155–8
  100. Barker WC et al (2000) The protein information resource (PIR). Nucleic Acids Res 28:41–4
  101. Mewes HW et al (2000) MIPS: a database for genomes and protein sequences. Nucleic Acids Res 28:37–40
  102. Scharfe C, Zaccaria P, Hoertnagel K, Jaksch M, Klopstock T, Lill R, Prokisch H, Gerbitz KD, Mewes HW and Meitinger T (1999) MITOP: database for mitochondria-related proteins, genes and diseases. Nucleic Acids Res 27:153–5
  103. Mewes HW, Heumann K, Kaps A, Mayer K, Pfeiffer F, Stocker S and Frishman D (1999) MIPS: a database for genomes and protein sequences. Nucleic Acid Res 27:44–8
  104. Frishman D and Mewes HW (1999) Genome-based structural biology. Prog Biophys Mol Biol 72:1–17
  105. Entian KD et al (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262:683–702
  106. Bevan M, Bancroft I, Mewes HW, Martienssen R and McCombie R (1999) Clearing a path through the jungle: progress in Arabidopsis genomics. Bioessays 21:110–20
  107. Barker WC et al (1999) The PIR-International Protein Sequence Database. Nucleic Acids Res 27:39–43
  108. Mewes HW, Hani J, Pfeiffer F and Frishman D (1998) MIPS: a database for protein sequences and complete genomes. Nucleic Acids Res 26:33–7
  109. Mewes HW, Frishman D, Zollner A and Heumann K (1998) The Bioinformatics of the Yeast Genome. In Brown AJP and Tuite MF, eds. Yeast Gene Analysis. Methods in Microbiology ed. Volume 26. Academic Press, Burlington, p 33–52
  110. Frishman D, Mironov A, Mewes HW and Gelfand M (1998) Combining diverse evidence for gene recognition in completely sequenced bacterial genomes. Nucleic Acids Res 26:2941–7
  111. Frishman D, Heumann K, Lesk A and Mewes HW (1998) Comprehensive, comprehensible, distributed and intelligent databases: current status. Bioinformatics 14:551–61
  112. Bevan M et al (1998) Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. Nature 391:485–8
  113. Barker WC et al (1998) The PIR-International Protein Sequence Database. Nucleic Acids Res 26:27–32
  114. Mewes HW, Albermann K, Heumann K, Liebl S and Pfeiffer F (1997) MIPS: a database for protein sequences, homology data and yeast genome information. Nucleic Acids Res 25:28–30
  115. Mewes HW et al (1997) Overview of the yeast genome. Nature 387:7–65
  116. Kaps A, Heumann K, Frishman D, Bähr M and Mewes HW (1997) Visualization and Analysis of the Complete Yeast Genome. In Hofestädt R, Lengauer T, Löffler M and Schomburg D, eds. Bioinformatics. Lecture Notes in Computer Science Volume 1278. Springer-Verlag, Berlin Heidelberg, p 178–88
  117. Kammerer S, Arnold N, Gutensohn W, Mewes HW, Kunau WH, Hofler G, Roscher AA and Braun A (1997) Genomic organization and molecular characterization of a gene encoding HsPXF, a human peroxisomal farnesylated protein. Genomics 45:200–10
  118. Jacq C et al (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Nature 387:75–8
  119. Tettelin H et al (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. Nature 387:81–4
  120. Johnston M et al (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. Nature 387:87–90
  121. Philippsen P et al (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Nature 387:93–8
  122. Dujon B et al (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. Nature 387:98–102
  123. Bussey H et al (1997) The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. Nature 387:103–5
  124. Heumann K et al (1997) The Yeast Genome CD-ROM. Nature
  125. Frishman D and Mewes HW (1997) Protein structural classes in five complete genomes. Nat Struct Biol 4:626–8
  126. Frishman D and Mewes HW (1997) PEDANTic genome analysis. Trends Genet 13:415–6
  127. Boehm S, Frishman D and Mewes HW (1997) Variations of the C2H2 zinc finger motif in the yeast genome. Nucleic Acids Res 25:2464–9
  128. Mewes HW, Baehr M, Zollner A and Heumann K (1996) The complete sequence of S. cerevisiae a dynamic data resource. Microb Comp Genomics 1:204
  129. Heumann K and Mewes HW (1996) The Hashed Position Tree (HPT): A Suffix Tree Variant for Large Data Sets Stored on Slow Mass Storage Devices. In Ziviani N, Baeza-Yates A and Guimaraes G, eds. Proceedings of the Third South American Workshop on String Processing, p 101–15
  130. Heumann K, Harris C and Mewes HW (1996) A top-down approach to whole genome visualization. Proc Int Conf Intell Sys Mol Biol 4:98–108
  131. Goffeau A et al (1996) Life with 6000 genes. Science 274:546,563–7
  132. George DG, Barker WC, Mewes HW, Pfeiffer F and Tsugita A (1996) The PIR-International Protein Sequence Database. Nucleic Acids Res 24:17–20
  133. Galibert F et al (1996) Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. EMBO J 15:2031–49
  134. Vassarotti A, Dujon B, Mordant P, Feldmann H, Mewes HW and Goffeau A (1995) Structure and organization of the European Yeast Genome Sequencing Network. J Biotechnol 41:131–7
  135. Mewes HW and Heumann K (1995) Genome Analysis: Pattern Search in Biological Macromolecules. In Galil Z and Ukkonen E, eds. Combinatorial Pattern Matching, 6th Annual Symposium Proceedings. Lecture Notes in Computer Science Volume 937. Springer-Verlag, Berlin Heidelberg, p 261–85
  136. Heumann K, Harris C, Kaps A, Liebl S, Maierl A, Pfeiffer F and Mewes HW (1995) An Integrated Services Approach to Biological Sequence Databases. In Schomburg D and Lessel U, eds. Bioinformatics: From Nucleic Acids and Proteins to Cell Metabolism. GBF, Braunschweig
  137. Mewes HW, Doelz R and George DG (1994) Sequence databases: an indespensible source for biotechnological research. J Biotechnol 35:239–56
  138. Heumann K, George D and Mewes HW (1994) A new concept of sequence data distribution on wide area networks. Comput Appl Biosci 10:519–26
  139. George DG, Barker WC, Mewes HW, Pfeiffer F and Tsugita A (1994) The PIR-International Protein Sequence Database. Nucleic Acids Res 22:3569–73
  140. Feldmann H et al (1994) Complete DNA sequence of yeast chromosome II. EMBO J 13:5795–809
  141. Dujon B et al (1994) Complete DNA sequence of yeast chromosome XI. Nature 396:371–8
  142. George DG, Orcutt BC, Mewes HW and Tsugita A (1993) An object-oriented sequence database definition language (SDDL). Prot Seq Data Anal 5:357–99
  143. Barker WC, George DG, Mewes HW, Pfeiffer F and Tsugita A (1993) The PIR-International databases. Nucleic Acids Res 21:3089–92
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